Juventus claimed a 2-1 away victory against Napoli on Sunday, to open a 16-point gap at the top of Serie A.
The Italian champions scored twice in the first half through Miralem Pjanic and Emre Can.
Jose Callejon pulled one back for the hosts just after the hour mark, but they failed to draw level in the second half.
Both sides were reduced to 10 men, with Lorenzo Insigne crashing an 84th-minute penalty against the post.
The win has almost certainly wrapped up an eighth straight title for the unbeaten Turin giants, who have 72 points out of a possible 78, with 12 games left.
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