Real Madrid were denied a first home win over city rivals, Atletico Madrid, in four attempts, after Antoine Griezmann struck late at the Santiago Bernabeu on Saturday.
Pepe opened scoring for Zinedine Zidane’s men, powering in a header from Toni Kroos’ expertly flighted free-kick.
Cristiano Ronaldo and Karim Benzema had chances to extend Real’s lead, but failed to beat Jan Oblak, who was in inspired form for the visitors in goal.
Atletico did not trouble the hosts too much until Griezmann levelled with his 15th league goal of the season.
The draw sees Madrid move three points clear of champions Barcelona, who face Malaga later on Saturday.
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